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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TBX5 HGNC:11604 (HGNC)
6910 (Entrez Gene)
601620 (OMIM)
TBX5 (gene) (MyGene.info)
HGNC homology
Chr12 q24.21 Chr12:114353911-114408708 (-)
Holt-Oram syndrome
Q99593 (UniProt | EBI)
NM_000192 (RefSeq)
mouse Tbx5 MGI:102541 (MGI)
21388 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 60.42 cM Chr5:119832668-119885219 (+)
Holt-Oram syndrome
OTTMUSG00000056236 (VEGA)
OTTMUSP00000072981 (VEGA)
OTTMUST00000138983 (VEGA)
rat Tbx5 304514 (Entrez Gene)
Chr12 q16 Q5I2P1 (UniProt | EBI)
NM_001009964 (RefSeq)
chimpanzee TBX5 452276 (Entrez Gene)
Chr12 XP_509400 (RefSeq)
cattle TBX5 532970 (Entrez Gene)
Chr17 NP_001179678 (RefSeq)
NM_001192749 (RefSeq)
dog TBX5 491447 (Entrez Gene)
Chr26 XP_013963523 (RefSeq)
chicken TBX5 373988 (Entrez Gene)
Chr15 Q9PWE8 (UniProt | EBI)
NM_204173 (RefSeq)
zebrafish tbx5a 30071 (Entrez Gene)
Chr5 Q9IAK8 (UniProt | EBI)
NM_001313682 (RefSeq)
frog, western clawed tbx5 619589 (Entrez Gene)
Chr1 Q3SA47 (UniProt | EBI)
NM_001198768 (RefSeq)
macaque, rhesus TBX5 713550 (Entrez Gene)
Chr11 XP_015008378 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory