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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HMBS HGNC:4982 (HGNC)
3145 (Entrez Gene)
609806 (OMIM)
Porphobilinogen deaminase (MyGene.info)
HGNC homology
Chr11 q23.3 Chr11:119084871-119093549 (+)
acute intermittent porphyria
P08397 (UniProt | EBI)
NM_001258209 (RefSeq)
mouse Hmbs MGI:96112 (MGI)
15288 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 24.84 cM Chr9:44336348-44344228 (-)
acute intermittent porphyria
15288 (NCBI Gene Model)
P22907 (UniProt | EBI)
NM_013551 (RefSeq)
rat Hmbs 25709 (Entrez Gene)
Chr8 q22 P19356 (UniProt | EBI)
NM_013168 (RefSeq)
cattle HMBS 515614 (Entrez Gene)
Chr15 Q2KIN5 (UniProt | EBI)
NM_001046207 (RefSeq)
dog HMBS 489373 (Entrez Gene)
Chr5 XP_013968850 (RefSeq)
chicken HMBS 419701 (Entrez Gene)
Chr24 XP_015153561 (RefSeq)
zebrafish hmbsa 394129 (Entrez Gene)
Chr5 NP_957448 (RefSeq)
NM_201154 (RefSeq)
hmbsb 338290 (Entrez Gene)
Chr15 NP_001019559 (RefSeq)
NM_001024388 (RefSeq)
frog, western clawed hmbs 448096 (Entrez Gene)
Chr7 NP_001005635 (RefSeq)
NM_001005635 (RefSeq)
macaque, rhesus HMBS 702943 (Entrez Gene)
Chr14 NP_001253589 (RefSeq)
NM_001266660 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory