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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
1577

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GRN HGNC:4601 (HGNC)
2896 (Entrez Gene)
138945 (OMIM)
Chr17 q21.32 Chr17:44345123-44353106 (+)
GRCh38
Ceroid Lipofuscinosis, Neuronal, 11; CLN11
Frontotemporal Lobar Degeneration with Tdp43 Inclusions, Grn-Related
P28799 (UniProt | EBI)
NM_002087 (RefSeq)
mouse Grn MGI:95832 (MGI)
14824 (Entrez Gene)
Gene Tree
VISTA-Point
Chr11 66.29 cM Chr11:102430315-102437048 (+)
GRCm38
OTTMUSG00000002816 (VEGA)
OTTMUSP00000002716 (VEGA)
OTTMUST00000005699 (VEGA)
rat Grn 29143 (Entrez Gene)
Chr10 q32.1 P23785 (UniProt | EBI)
NM_017113 (RefSeq)
chimpanzee GRN 454728 (Entrez Gene)
Chr17 XP_009430296 (RefSeq)
NM_001280142 (RefSeq)
rhesus macaque LOC714851 714851 (Entrez Gene)
Chr16 XP_002808178 (RefSeq)
cattle GRN 767942 (Entrez Gene)
Chr19 NP_001070482 (RefSeq)
NM_001077014 (RefSeq)
western clawed frog grn 594884 (Entrez Gene)
ChrUN NP_001072169 (RefSeq)
NM_001078701 (RefSeq)
zebrafish grna 791524 (Entrez Gene)
Chr3 NP_001001949 (RefSeq)
NM_001001949 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory