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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPECC1L HGNC:29022 (HGNC)
23384 (Entrez Gene)
614140 (OMIM)
HGNC homology
Chr22 q11.23 Chr22:24270817-24417740 (+)
Opitz-GBBB syndrome
Q69YQ0 (UniProt | EBI)
NM_001254733 (RefSeq)
mouse Specc1l MGI:1921642 (MGI)
74392 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 38.51 cM Chr10:75212037-75312400 (+)
74392 (NCBI Gene Model)
Q2KN98 (UniProt | EBI)
NM_001145826 (RefSeq)
rat Specc1l 361828 (Entrez Gene)
Chr20 p12 Q2KN99 (UniProt | EBI)
NM_001039455 (RefSeq)
chimpanzee SPECC1L 458713 (Entrez Gene)
Chr22 Q2KNA1 (UniProt | EBI)
NM_001039963 (RefSeq)
cattle SPECC1L 519751 (Entrez Gene)
Chr17 NP_001192793 (RefSeq)
NM_001205864 (RefSeq)
dog SPECC1L 486397 (Entrez Gene)
Chr26 Q2KNA0 (UniProt | EBI)
NM_001048114 (RefSeq)
chicken SPECC1L 416950 (Entrez Gene)
Chr15 Q2KN97 (UniProt | EBI)
NM_001044637 (RefSeq)
zebrafish specc1la 561775 (Entrez Gene)
Chr8 Q2KN93 (UniProt | EBI)
NM_001039816 (RefSeq)
frog, western clawed specc1l 733457 (Entrez Gene)
Chr1 Q2KN96 (UniProt | EBI)
NM_001044410 (RefSeq)
macaque, rhesus SPECC1L 707641 (Entrez Gene)
Chr10 NP_001244848 (RefSeq)
NM_001257919 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory