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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPPL3 HGNC:30424 (HGNC)
121665 (Entrez Gene)
608240 (OMIM)
UNQ1887 (MyGene.info)
HGNC homology
Chr12 q24.31 Chr12:120762510-120904352 (-)
Q8TCT6 (UniProt | EBI)
NM_139015 (RefSeq)
mouse Sppl3 MGI:1891433 (MGI)
74585 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 55.99 cM Chr5:115011524-115098790 (+)
74585 (NCBI Gene Model)
Q9CUS9 (UniProt | EBI)
NM_029012 (RefSeq)
rat Sppl3 360822 (Entrez Gene)
Chr12 q16 XP_006221487 (RefSeq)
chimpanzee SPPL3 452314 (Entrez Gene)
Chr12 NP_001233544 (RefSeq)
NM_001246615 (RefSeq)
cattle SPPL3 535156 (Entrez Gene)
Chr17 XP_024833558 (RefSeq)
dog SPPL3 486301 (Entrez Gene)
Chr26 XP_022266508 (RefSeq)
chicken SPPL3 416968 (Entrez Gene)
Chr15 XP_004934435 (RefSeq)
zebrafish sppl3 548609 (Entrez Gene)
Chr10 NP_001015068 (RefSeq)
NM_001015068 (RefSeq)
frog, western clawed sppl3 394539 (Entrez Gene)
Chr1 NP_988942 (RefSeq)
NM_203611 (RefSeq)
macaque, rhesus SPPL3 700898 (Entrez Gene)
Chr11 NP_001253621 (RefSeq)
NM_001266692 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory