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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FMR1 HGNC:3775 (HGNC)
2332 (Entrez Gene)
309550 (OMIM)
FMR1 (MyGene.info)
HGNC homology
ChrX q27.3 ChrX:147911951-147951127 (+)
fragile X-associated tremor/ataxia syndrome
fragile X syndrome
premature ovarian failure
Q06787 (UniProt | EBI)
NM_002024 (RefSeq)
mouse Fmr1 MGI:95564 (MGI)
14265 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 34.83 cM ChrX:68678541-68717963 (+)
autistic disorder
fragile X-associated tremor/ataxia syndrome
fragile X syndrome
OTTMUSG00000017748 (VEGA)
OTTMUSP00000019323 (VEGA)
OTTMUST00000042972 (VEGA)
rat Fmr1 24948 (Entrez Gene)
ChrX Q80WE1 (UniProt | EBI)
NM_052804 (RefSeq)
chimpanzee FMR1 465894 (Entrez Gene)
ChrX XP_009438010 (RefSeq)
cattle FMR1 507482 (Entrez Gene)
ChrX NP_001179079 (RefSeq)
NM_001192150 (RefSeq)
dog FMR1 481070 (Entrez Gene)
ChrX XP_005641964 (RefSeq)
chicken FMR1 422395 (Entrez Gene)
Chr4 XP_015140747 (RefSeq)
zebrafish fmr1 259191 (Entrez Gene)
Chr14 NP_694495 (RefSeq)
NM_152963 (RefSeq)
frog, western clawed fmr1 448049 (Entrez Gene)
Chr8 Q6GLC9 (UniProt | EBI)
NM_001005454 (RefSeq)
macaque, rhesus FMR1 700138 (Entrez Gene)
ChrX XP_014983849 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory