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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
149

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MSH6 HGNC:7329 (HGNC)
2956 (Entrez Gene)
600678 (OMIM)
Chr2 p16 Chr2:47783082-47806953 (+)
GRCh38
Colorectal Cancer, Hereditary Nonpolyposis, Type 5; HNPCC5
Endometrial Cancer
Mismatch Repair Cancer Syndrome; MMRCS
P52701 (UniProt | EBI)
NM_000179 (RefSeq)
mouse Msh6 MGI:1343961 (MGI)
17688 (Entrez Gene)
Gene Tree
VISTA-Point
Chr17 57.87 cM Chr17:87975050-87990883 (+)
GRCm38
ENSMUSG00000005370 (Ensembl Gene Model)
ENSMUSP00000005503 (Ensembl)
ENSMUST00000005503 (Ensembl)
rat LOC100360342 100360342 (Entrez Gene)
Chr6 XP_006225731 (RefSeq)
chimpanzee MSH6 459218 (Entrez Gene)
Chr2A XP_003309101 (RefSeq)
rhesus macaque MSH6 715701 (Entrez Gene)
Chr13 NP_001253005 (RefSeq)
NM_001266076 (RefSeq)
cattle MSH6 540526 (Entrez Gene)
Chr11 NP_001179666 (RefSeq)
NM_001192737 (RefSeq)
dog MSH6 474585 (Entrez Gene)
Chr10 XP_531814 (RefSeq)
chicken MSH6 421291 (Entrez Gene)
Chr3 XP_419359 (RefSeq)
zebrafish msh6 260437 (Entrez Gene)
Chr13 NP_878280 (RefSeq)
NM_182860 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory