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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EDNRA HGNC:3179 (HGNC)
1909 (Entrez Gene)
131243 (OMIM)
Endothelin receptor type A (MyGene.info)
HGNC homology
Chr4 q31.22-q31.23 Chr4:147480917-147544954 (+)
mandibulofacial dysostosis with alopecia
P25101 (UniProt | EBI)
NM_001166055 (RefSeq)
mouse Ednra MGI:105923 (MGI)
13617 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 36.63 cM Chr8:77663029-77724452 (-)
mandibulofacial dysostosis with alopecia
velocardiofacial syndrome
13617 (NCBI Gene Model)
Q61614 (UniProt | EBI)
NM_010332 (RefSeq)
rat Ednra 24326 (Entrez Gene)
Chr19 q11 P26684 (UniProt | EBI)
NM_012550 (RefSeq)
chimpanzee EDNRA 461530 (Entrez Gene)
Chr4 XP_001149597 (RefSeq)
cattle EDNRA 281749 (Entrez Gene)
Chr17 P21450 (UniProt | EBI)
NM_174308 (RefSeq)
dog EDNRA 450187 (Entrez Gene)
Chr15 Q5KSU9 (UniProt | EBI)
NM_001031632 (RefSeq)
chicken EDNRA 373908 (Entrez Gene)
Chr4 NP_989450 (RefSeq)
NM_204119 (RefSeq)
zebrafish ednraa 114550 (Entrez Gene)
Chr1 NP_001092915 (RefSeq)
NM_001099445 (RefSeq)
frog, western clawed ednra 779728 (Entrez Gene)
Chr1 NP_001072275 (RefSeq)
NM_001078807 (RefSeq)
macaque, rhesus EDNRA 704135 (Entrez Gene)
Chr5 NP_001248421 (RefSeq)
NM_001261492 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory