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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DSG2 HGNC:3049 (HGNC)
1829 (Entrez Gene)
125671 (OMIM)
Desmoglein 2 (MyGene.info)
HGNC homology
Chr18 q12.1 Chr18:31498004-31549008 (+)
arrhythmogenic right ventricular dysplasia 10
dilated cardiomyopathy 1BB
Q14126 (UniProt | EBI)
NM_001943 (RefSeq)
mouse Dsg2 MGI:1196466 (MGI)
13511 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 11.42 cM Chr18:20558074-20604521 (+)
OTTMUSG00000030073 (VEGA)
OTTMUSP00000038847 (VEGA)
OTTMUST00000074515 (VEGA)
rat Dsg2 307562 (Entrez Gene)
Chr18 p12 XP_006254536 (RefSeq)
chimpanzee DSG2 455356 (Entrez Gene)
Chr18 XP_512079 (RefSeq)
cattle DSG2 508151 (Entrez Gene)
Chr24 NP_001179101 (RefSeq)
NM_001192172 (RefSeq)
dog DSG2 490500 (Entrez Gene)
Chr7 XP_005622989 (RefSeq)
chicken DSG2 428529 (Entrez Gene)
Chr2 XP_426083 (RefSeq)
zebrafish dsg2.1 560026 (Entrez Gene)
Chr20 NP_001243566 (RefSeq)
NM_001256637 (RefSeq)
dsg2l 100884140 (Entrez Gene)
Chr2 XP_005171176 (RefSeq)
si:ch73-74h11.1 100534918 (Entrez Gene)
Chr20 XP_017208205 (RefSeq)
zmp:0000001074 101882022 (Entrez Gene)
Chr20 XP_021324275 (RefSeq)
frog, western clawed dsg2 100495580 (Entrez Gene)
Chr6 XP_017950382 (RefSeq)
macaque, rhesus DSG2 705805 (Entrez Gene)
Chr18 XP_001098597 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory