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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DENND5A HGNC:19344 (HGNC)
23258 (Entrez Gene)
617278 (OMIM)
HGNC homology
Chr11 p15.4 Chr11:9138825-9265335 (-)
early infantile epileptic encephalopathy 49
Q6IQ26 (UniProt | EBI)
NM_001348750 (RefSeq)
mouse Dennd5a MGI:1201681 (MGI)
19347 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 57.62 cM Chr7:109893780-109960470 (-)
19347 (NCBI Gene Model)
Q6PAL8 (UniProt | EBI)
NM_021494 (RefSeq)
rat Dennd5a 308942 (Entrez Gene)
Chr1 q33 G3V7Q0 (UniProt | EBI)
NM_001107546 (RefSeq)
chimpanzee DENND5A 451734 (Entrez Gene)
Chr11 XP_016775841 (RefSeq)
cattle DENND5A 784484 (Entrez Gene)
Chr15 XP_024831576 (RefSeq)
dog DENND5A 476844 (Entrez Gene)
Chr21 XP_005633713 (RefSeq)
chicken DENND5A 423048 (Entrez Gene)
Chr5 XP_015141955 (RefSeq)
zebrafish dennd5a 799847 (Entrez Gene)
Chr7 XP_005166668 (RefSeq)
frog, western clawed dennd5a 100158564 (Entrez Gene)
ChrUN NP_001121468 (RefSeq)
NM_001127996 (RefSeq)
macaque, rhesus DENND5A 707945 (Entrez Gene)
Chr14 XP_028689533 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory