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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TRIM50 HGNC:19017 (HGNC)
135892 (Entrez Gene)
612548 (OMIM)
HGNC homology
Chr7 q11.23 Chr7:73312536-73328082 (-)
Q86XT4 (UniProt | EBI)
NM_178125 (RefSeq)
mouse Trim50 MGI:2664992 (MGI)
215061 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 75.15 cM Chr5:135353295-135368005 (+)
ENSMUSG00000053388 (Ensembl Gene Model)
ENSMUSP00000106811 (Ensembl)
ENSMUST00000111180 (Ensembl)
rat Trim50 288596 (Entrez Gene)
Chr12 q12 Q810I1 (UniProt | EBI)
NM_181080 (RefSeq)
chimpanzee TRIM50 472403 (Entrez Gene)
Chr7 XP_527777 (RefSeq)
cattle TRIM50 616685 (Entrez Gene)
Chr25 NP_001193185 (RefSeq)
NM_001206256 (RefSeq)
dog TRIM50 489811 (Entrez Gene)
Chr6 XP_022275278 (RefSeq)
chicken TRIM74 417461 (Entrez Gene)
Chr19 XP_015151390 (RefSeq)
frog, western clawed trim50 100495882 (Entrez Gene)
Chr5 XP_017949750 (RefSeq)
macaque, rhesus TRIM50 716264 (Entrez Gene)
Chr3 XP_028701505 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory