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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DBT HGNC:2698 (HGNC)
1629 (Entrez Gene)
248610 (OMIM)
DBT (gene) (MyGene.info)
HGNC homology
Chr1 p21.2 Chr1:100186922-100249864 (-)
maple syrup urine disease
P11182 (UniProt | EBI)
NM_001918 (RefSeq)
mouse Dbt MGI:105386 (MGI)
13171 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 50.37 cM Chr3:116513075-116549981 (+)
maple syrup urine disease
13171 (NCBI Gene Model)
P53395 (UniProt | EBI)
NM_010022 (RefSeq)
rat Dbt 29611 (Entrez Gene)
Chr2 q41 NP_445764 (RefSeq)
NM_053312 (RefSeq)
chimpanzee DBT 457056 (Entrez Gene)
Chr1 NP_001136231 (RefSeq)
NM_001142759 (RefSeq)
cattle DBT 280759 (Entrez Gene)
Chr3 P11181 (UniProt | EBI)
NM_173905 (RefSeq)
dog DBT 479929 (Entrez Gene)
Chr6 XP_537055 (RefSeq)
chicken DBT 395374 (Entrez Gene)
Chr8 NP_989987 (RefSeq)
NM_204656 (RefSeq)
zebrafish dbt 541388 (Entrez Gene)
Chr22 NP_001013533 (RefSeq)
NM_001013515 (RefSeq)
frog, western clawed dbt 549717 (Entrez Gene)
Chr4 NP_001016963 (RefSeq)
NM_001016963 (RefSeq)
macaque, rhesus DBT 711547 (Entrez Gene)
Chr1 NP_001248206 (RefSeq)
NM_001261277 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory