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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NEK1 HGNC:7744 (HGNC)
4750 (Entrez Gene)
604588 (OMIM)
NEK1 (MyGene.info)
HGNC homology
Chr4 q33 Chr4:169393270-169612629 (-)
short-rib thoracic dysplasia 6 with or without polydactyly
Q96PY6 (UniProt | EBI)
NM_001199399 (RefSeq)
mouse Nek1 MGI:97303 (MGI)
18004 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 30.91 cM Chr8:60993195-61131346 (+)
autosomal recessive polycystic kidney disease
OTTMUSG00000031430 (VEGA)
OTTMUSP00000077359 (VEGA)
OTTMUST00000148962 (VEGA)
rat Nek1 290705 (Entrez Gene)
Chr16 p12 NP_001099552 (RefSeq)
NM_001106082 (RefSeq)
chimpanzee NEK1 471345 (Entrez Gene)
Chr4 XP_526727 (RefSeq)
cattle NEK1 534671 (Entrez Gene)
Chr8 XP_010805980 (RefSeq)
dog NEK1 486058 (Entrez Gene)
Chr25 XP_013963041 (RefSeq)
chicken NEK1 422433 (Entrez Gene)
Chr4 XP_015140867 (RefSeq)
zebrafish nek1 556002 (Entrez Gene)
Chr20 XP_009292953 (RefSeq)
frog, western clawed nek1 100036653 (Entrez Gene)
Chr1 NP_001090680 (RefSeq)
NM_001097211 (RefSeq)
macaque, rhesus NEK1 694345 (Entrez Gene)
Chr5 XP_014994979 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory