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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CTNNB1 HGNC:2514 (HGNC)
1499 (Entrez Gene)
116806 (OMIM)
Beta-catenin (MyGene.info)
HGNC homology
Chr3 p22.1 Chr3:41199451-41240448 (+)
autosomal dominant non-syndromic intellectual disability 19
colorectal cancer
exudative vitreoretinopathy 7
hepatocellular carcinoma
ovarian cancer
P35222 (UniProt | EBI)
NM_001098210 (RefSeq)
mouse Ctnnb1 MGI:88276 (MGI)
12387 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 72.19 cM Chr9:120929216-120960507 (+)
autistic disorder
granulosa cell tumor
ovarian cancer
prostate cancer
urinary bladder cancer
OTTMUSG00000016490 (VEGA)
OTTMUSP00000017750 (VEGA)
OTTMUST00000039790 (VEGA)
rat Ctnnb1 84353 (Entrez Gene)
Chr8 q32 Q9WU82 (UniProt | EBI)
NM_053357 (RefSeq)
chimpanzee CTNNB1 450183 (Entrez Gene)
Chr3 XP_024211190 (RefSeq)
cattle CTNNB1 539003 (Entrez Gene)
Chr22 Q0VCX4 (UniProt | EBI)
NM_001076141 (RefSeq)
dog CTNNB1 477032 (Entrez Gene)
Chr23 B6V8E6 (UniProt | EBI)
NM_001137652 (RefSeq)
chicken CTNNB1 395964 (Entrez Gene)
Chr2 NP_990412 (RefSeq)
NM_205081 (RefSeq)
zebrafish ctnnb1 30265 (Entrez Gene)
Chr16 NP_571134 (RefSeq)
NM_131059 (RefSeq)
frog, western clawed ctnnb1 549712 (Entrez Gene)
Chr6 NP_001016958 (RefSeq)
NM_001016958 (RefSeq)
macaque, rhesus CTNNB1 574265 (Entrez Gene)
Chr2 NP_001244847 (RefSeq)
NM_001257918 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory