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HomoloGene Vertebrate Homology
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
14260

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ISCA2 HGNC:19857 (HGNC)
122961 (Entrez Gene)
615317 (OMIM)
HGNC homology
Chr14 q24.3 Chr14:74493720-74495568 (+)
GRCh38.p7
multiple mitochondrial dysfunctions syndrome 4
Q86U28 (UniProt | EBI)
NM_194279 (RefSeq)
mouse Isca2 MGI:1921566 (MGI)
74316 (Entrez Gene)
Gene Tree
VISTA-Point
HGNC homology
Chr12 39.38 cM Chr12:84773251-84775088 (+)
GRCm38
ENSMUSG00000021241 (Ensembl Gene Model)
ENSMUSP00000021667 (Ensembl)
ENSMUST00000021667 (Ensembl)
rat Isca2 500694 (Entrez Gene)
Chr6 q31 NP_001102748 (RefSeq)
NM_001109278 (RefSeq)
chimpanzee ISCA2 740854 (Entrez Gene)
Chr14 XP_001143075 (RefSeq)
cattle ISCA2 613290 (Entrez Gene)
Chr10 Q2TBG7 (UniProt | EBI)
NM_001038683 (RefSeq)
dog ISCA2 490783 (Entrez Gene)
Chr8 XP_547905 (RefSeq)
chicken ISCA2 423352 (Entrez Gene)
Chr5 XP_025007072 (RefSeq)
zebrafish isca2 100150438 (Entrez Gene)
Chr17 NP_001314830 (RefSeq)
NM_001327901 (RefSeq)
frog, western clawed isca2 100135112 (Entrez Gene)
Chr8 XP_002938644 (RefSeq)
macaque, rhesus ISCA2 700004 (Entrez Gene)
Chr7 NP_001247936 (RefSeq)
NM_001261007 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/09/2019
MGI 6.13
The Jackson Laboratory