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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GLI3 HGNC:4319 (HGNC)
2737 (Entrez Gene)
165240 (OMIM)
GLI3 (MyGene.info)
HGNC homology
Chr7 p14.1 Chr7:41960949-42237019 (-)
esophageal atresia/tracheoesophageal fistula
Greig cephalopolysyndactyly syndrome
Pallister-Hall syndrome
P10071 (UniProt | EBI)
NM_000168 (RefSeq)
mouse Gli3 MGI:95729 (MGI)
14634 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 5.43 cM Chr13:15463235-15730026 (+)
Greig cephalopolysyndactyly syndrome
Pallister-Hall syndrome
OTTMUSG00000024401 (VEGA)
OTTMUSP00000029127 (VEGA)
OTTMUST00000059816 (VEGA)
rat Gli3 140588 (Entrez Gene)
Chr17 q12.1 NP_536330 (RefSeq)
NM_080405 (RefSeq)
chimpanzee GLI3 463369 (Entrez Gene)
Chr7 Q5IS56 (UniProt | EBI)
NM_001034190 (RefSeq)
cattle GLI3 785371 (Entrez Gene)
Chr4 XP_005205716 (RefSeq)
dog GLI3 483244 (Entrez Gene)
Chr18 XP_013976300 (RefSeq)
chicken GLI3 420769 (Entrez Gene)
Chr2 Q9IA31 (UniProt | EBI)
NM_001271903 (RefSeq)
zebrafish gli3 403042 (Entrez Gene)
Chr24 NP_991291 (RefSeq)
NM_205728 (RefSeq)
frog, western clawed gli3 100101789 (Entrez Gene)
Chr6 XP_004915407 (RefSeq)
macaque, rhesus GLI3 702494 (Entrez Gene)
Chr3 XP_014989159 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory