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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GLI3 HGNC:4319 (HGNC)
2737 (Entrez Gene)
165240 (OMIM)
Chr7 p13 Chr7:41960949-42237870 (-)
Greig Cephalopolysyndactyly Syndrome; GCPS
Hypothalamic Hamartomas
Pallister-Hall Syndrome; PHS
Polydactyly, Postaxial, Type A1; PAPA1
Polydactyly, Preaxial IV
Tracheoesophageal Fistula with or without Esophageal Atresia
P10071 (UniProt | EBI)
NM_000168 (RefSeq)
mouse Gli3 MGI:95729 (MGI)
14634 (Entrez Gene)
Gene Tree
Chr13 5.43 cM Chr13:15463235-15730026 (+)
Greig Cephalopolysyndactyly Syndrome; GCPS
Pallister-Hall Syndrome; PHS
OTTMUSG00000024401 (VEGA)
OTTMUSP00000029127 (VEGA)
OTTMUST00000059816 (VEGA)
rat Gli3 140588 (Entrez Gene)
Chr17 q12.1 NP_536330 (RefSeq)
NM_080405 (RefSeq)
chimpanzee GLI3 463369 (Entrez Gene)
Chr7 Q5IS56 (UniProt | EBI)
NM_001034190 (RefSeq)
rhesus macaque GLI3 702494 (Entrez Gene)
Chr3 XP_001097931 (RefSeq)
cattle GLI3 785371 (Entrez Gene)
Chr4 XP_001253426 (RefSeq)
dog GLI3 483244 (Entrez Gene)
Chr18 XP_540363 (RefSeq)
chicken GLI3 420769 (Entrez Gene)
Chr2 Q9IA31 (UniProt | EBI)
NM_001271903 (RefSeq)
western clawed frog gli3 100101789 (Entrez Gene)
ChrUN XP_004915407 (RefSeq)
zebrafish gli3 403042 (Entrez Gene)
Chr24 NP_991291 (RefSeq)
NM_205728 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory