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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CTSC HGNC:2528 (HGNC)
1075 (Entrez Gene)
602365 (OMIM)
Cathepsin C (MyGene.info)
HGNC homology
Chr11 q14.2 Chr11:88293592-88337787 (-)
aggressive periodontitis
Papillon-Lefevre disease
P53634 (UniProt | EBI)
NM_001114173 (RefSeq)
mouse Ctsc MGI:109553 (MGI)
13032 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 49.11 cM Chr7:88278085-88310888 (+)
OTTMUSG00000031137 (VEGA)
OTTMUSP00000040719 (VEGA)
OTTMUST00000077133 (VEGA)
rat Ctsc 25423 (Entrez Gene)
Chr1 q32 P80067 (UniProt | EBI)
NM_017097 (RefSeq)
chimpanzee CTSC 451469 (Entrez Gene)
Chr11 XP_508684 (RefSeq)
cattle CTSC 352958 (Entrez Gene)
Chr29 Q3ZCJ8 (UniProt | EBI)
NM_001033617 (RefSeq)
dog CTSC 403458 (Entrez Gene)
Chr21 O97578 (UniProt | EBI)
NM_001195834 (RefSeq)
chicken CTSC 419014 (Entrez Gene)
Chr1 NP_001308483 (RefSeq)
NM_001321554 (RefSeq)
zebrafish ctsc 368704 (Entrez Gene)
Chr15 NP_999887 (RefSeq)
NM_214722 (RefSeq)
frog, western clawed ctsc 407938 (Entrez Gene)
Chr2 NP_001032336 (RefSeq)
NM_001037259 (RefSeq)
macaque, rhesus CTSC 705320 (Entrez Gene)
Chr14 NP_001182580 (RefSeq)
NM_001195651 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory