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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GJB1 HGNC:4283 (HGNC)
2705 (Entrez Gene)
304040 (OMIM)
GJB1 (MyGene.info)
HGNC homology
ChrX q13.1 ChrX:71215212-71225215 (+)
Charcot-Marie-Tooth disease X-linked dominant 1
P08034 (UniProt | EBI)
NM_000166 (RefSeq)
mouse Gjb1 MGI:95719 (MGI)
14618 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 44.06 cM ChrX:101376378-101385629 (+)
Charcot-Marie-Tooth disease X-linked dominant 1
OTTMUSG00000018210 (VEGA)
OTTMUSP00000019746 (VEGA)
OTTMUST00000043977 (VEGA)
rat Gjb1 29584 (Entrez Gene)
ChrX q22 P08033 (UniProt | EBI)
NM_017251 (RefSeq)
chimpanzee GJB1 465696 (Entrez Gene)
ChrX XP_521117 (RefSeq)
cattle GJB1 281194 (Entrez Gene)
ChrX Xq22 O18968 (UniProt | EBI)
NM_174069 (RefSeq)
dog GJB1 480953 (Entrez Gene)
ChrX XP_022271485 (RefSeq)
chicken GJB1 378797 (Entrez Gene)
Chr4 NP_989702 (RefSeq)
NM_204371 (RefSeq)
zebrafish cx31.7 100150195 (Entrez Gene)
Chr14 XP_001921623 (RefSeq)
frog, western clawed gjb1 407921 (Entrez Gene)
Chr8 NP_001001240 (RefSeq)
NM_001001240 (RefSeq)
macaque, rhesus GJB1 706327 (Entrez Gene)
ChrX NP_001244546 (RefSeq)
NM_001257617 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory