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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ABCB4 HGNC:45 (HGNC)
5244 (Entrez Gene)
171060 (OMIM)
ABCB4 (MyGene.info)
HGNC homology
Chr7 q21.12 Chr7:87399461-87475864 (-)
intrahepatic cholestasis
P21439 (UniProt | EBI)
NM_018849 (RefSeq)
mouse Abcb4 MGI:97569 (MGI)
18670 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 3.43 cM Chr5:8893717-8959231 (+)
hepatocellular carcinoma
intrahepatic cholestasis
primary sclerosing cholangitis
OTTMUSG00000054368 (VEGA)
OTTMUSP00000071491 (VEGA)
OTTMUST00000134885 (VEGA)
rat Abcb4 24891 (Entrez Gene)
Chr4 q12 Q08201 (UniProt | EBI)
NM_012690 (RefSeq)
chimpanzee ABCB4 748364 (Entrez Gene)
Chr7 XP_016813158 (RefSeq)
cattle ABCB4 100336913 (Entrez Gene)
Chr4 XP_010802433 (RefSeq)
dog ABCB4 482284 (Entrez Gene)
Chr14 XP_013974663 (RefSeq)
chicken ABCB1 395712 (Entrez Gene)
Chr2 NP_990225 (RefSeq)
NM_204894 (RefSeq)
ABCB1LA 420534 (Entrez Gene)
Chr2 XP_025004169 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory