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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GJA1 HGNC:4274 (HGNC)
2697 (Entrez Gene)
121014 (OMIM)
GJA1 (MyGene.info)
HGNC homology
Chr6 q22.31 Chr6:121435577-121449744 (+)
atrioventricular septal defect
craniometaphyseal dysplasia
erythrokeratodermia variabilis
hypoplastic left heart syndrome
oculodentodigital dysplasia
P17302 (UniProt | EBI)
NM_000165 (RefSeq)
mouse Gja1 MGI:95713 (MGI)
14609 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 28.64 cM Chr10:56377300-56390419 (+)
oculodentodigital dysplasia
14609 (NCBI Gene Model)
P23242 (UniProt | EBI)
NM_010288 (RefSeq)
rat Gja1 24392 (Entrez Gene)
Chr20 q11 P08050 (UniProt | EBI)
NM_012567 (RefSeq)
chimpanzee GJA1 744245 (Entrez Gene)
Chr6 XP_001164338 (RefSeq)
cattle GJA1 281193 (Entrez Gene)
Chr9 q15-q16 P18246 (UniProt | EBI)
NM_174068 (RefSeq)
dog GJA1 403418 (Entrez Gene)
Chr1 Q6S9C0 (UniProt | EBI)
NM_001002951 (RefSeq)
chicken GJA1 395278 (Entrez Gene)
Chr3 P14154 (UniProt | EBI)
NM_204586 (RefSeq)
zebrafish cx43 30236 (Entrez Gene)
Chr20 O57474 (UniProt | EBI)
NM_131038 (RefSeq)
frog, western clawed gja1 394450 (Entrez Gene)
Chr5 NP_988856 (RefSeq)
NM_203525 (RefSeq)
macaque, rhesus GJA1 714344 (Entrez Gene)
Chr4 NP_001247996 (RefSeq)
NM_001261067 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory