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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CYP46A1 HGNC:2641 (HGNC)
10858 (Entrez Gene)
604087 (OMIM)
CYP46A1 (MyGene.info)
HGNC homology
Chr14 q32.2 Chr14:99684262-99727321 (+)
Q9Y6A2 (UniProt | EBI)
NM_006668 (RefSeq)
mouse Cyp46a1 MGI:1341877 (MGI)
13116 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 59.41 cM Chr12:108334381-108362234 (+)
ENSMUSG00000021259 (Ensembl Gene Model)
ENSMUSP00000021684 (Ensembl)
ENSMUST00000021684 (Ensembl)
rat Cyp46a1 362782 (Entrez Gene)
Chr6 q32 NP_001102193 (RefSeq)
NM_001108723 (RefSeq)
chimpanzee CYP46A1 453154 (Entrez Gene)
Chr14 XP_016782209 (RefSeq)
cattle CYP46A1 506438 (Entrez Gene)
Chr21 NP_001070278 (RefSeq)
NM_001076810 (RefSeq)
dog CYP46A1 480432 (Entrez Gene)
Chr8 XP_022278175 (RefSeq)
chicken CYP46A1 423450 (Entrez Gene)
Chr5 NP_001238956 (RefSeq)
NM_001252027 (RefSeq)
frog, western clawed cyp46a1 780005 (Entrez Gene)
Chr8 NP_001072550 (RefSeq)
NM_001079082 (RefSeq)
mgc108077 613111 (Entrez Gene)
Chr8 NP_001027519 (RefSeq)
NM_001032348 (RefSeq)
mgc108213 613109 (Entrez Gene)
Chr8 NP_001027517 (RefSeq)
NM_001032346 (RefSeq)
macaque, rhesus LOC705843 705843 (Entrez Gene)
Chr7 XP_014999956 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory