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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GHR HGNC:4263 (HGNC)
2690 (Entrez Gene)
600946 (OMIM)
Growth hormone receptor (MyGene.info)
HGNC homology
Chr5 p13.1-p12 Chr5:42423775-42721878 (+)
familial hypercholesterolemia
Laron syndrome
P10912 (UniProt | EBI)
NM_001242405 (RefSeq)
mouse Ghr MGI:95708 (MGI)
14600 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 1.84 cM Chr15:3317755-3583352 (-)
Laron syndrome
14600 (NCBI Gene Model)
P16882 (UniProt | EBI)
NM_010284 (RefSeq)
rat Ghr 25235 (Entrez Gene)
Chr2 q16 P16310 (UniProt | EBI)
NM_017094 (RefSeq)
chimpanzee GHR 471560 (Entrez Gene)
Chr5 XP_024212389 (RefSeq)
cattle GHR 280805 (Entrez Gene)
Chr20 q17 O46600 (UniProt | EBI)
NM_176608 (RefSeq)
dog GHR 403721 (Entrez Gene)
Chr4 Q9TU69 (UniProt | EBI)
NM_001003123 (RefSeq)
chicken GHR 408184 (Entrez Gene)
ChrZ Q02092 (UniProt | EBI)
NM_001001293 (RefSeq)
zebrafish ghra 100001424 (Entrez Gene)
Chr8 NP_001077047 (RefSeq)
NM_001083578 (RefSeq)
frog, western clawed ghr 100493377 (Entrez Gene)
Chr1 XP_002933093 (RefSeq)
macaque, rhesus GHR 697986 (Entrez Gene)
Chr6 P79194 (UniProt | EBI)
NM_001042667 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory