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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SHMT2 HGNC:10852 (HGNC)
6472 (Entrez Gene)
138450 (OMIM)
Template:PBB/6472 (MyGene.info)
HGNC homology
Chr12 q13.3 Chr12:57229573-57234935 (+)
P34897 (UniProt | EBI)
NM_001166358 (RefSeq)
mouse Shmt2 MGI:1277989 (MGI)
108037 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 74.51 cM Chr10:127517123-127522444 (-)
108037 (NCBI Gene Model)
Q9CZN7 (UniProt | EBI)
NM_028230 (RefSeq)
rat Shmt2 299857 (Entrez Gene)
Chr7 q22 NP_001008323 (RefSeq)
NM_001008322 (RefSeq)
chimpanzee SHMT2 452007 (Entrez Gene)
Chr12 XP_016780365 (RefSeq)
cattle SHMT2 507197 (Entrez Gene)
Chr5 Q3SZ20 (UniProt | EBI)
NM_001034282 (RefSeq)
dog SHMT2 607458 (Entrez Gene)
Chr10 XP_849244 (RefSeq)
zebrafish shmt2 100144628 (Entrez Gene)
Chr6 NP_001116846 (RefSeq)
NM_001123374 (RefSeq)
frog, western clawed shmt2 493265 (Entrez Gene)
Chr2 NP_001007880 (RefSeq)
NM_001007879 (RefSeq)
macaque, rhesus SHMT2 714433 (Entrez Gene)
Chr11 XP_015007585 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory