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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACTA2 HGNC:130 (HGNC)
59 (Entrez Gene)
102620 (OMIM)
ACTA2 (MyGene.info)
HGNC homology
Chr10 q23.31 Chr10:88935074-88991397 (-)
Moyamoya disease
thoracic aortic aneurysm
P62736 (UniProt | EBI)
NM_001320855 (RefSeq)
mouse Acta2 MGI:87909 (MGI)
11475 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 29.41 cM Chr19:34241090-34255336 (-)
ENSMUSG00000035783 (Ensembl Gene Model)
ENSMUSP00000048218 (Ensembl)
ENSMUST00000039631 (Ensembl)
rat Acta2 81633 (Entrez Gene)
Chr1 P62738 (UniProt | EBI)
NM_031004 (RefSeq)
chimpanzee ACTA2 466148 (Entrez Gene)
Chr10 XP_001141780 (RefSeq)
cattle ACTA2 515610 (Entrez Gene)
Chr26 P62739 (UniProt | EBI)
NM_001034502 (RefSeq)
dog ACTA2 477587 (Entrez Gene)
Chr26 XP_534781 (RefSeq)
chicken ACTA2 423787 (Entrez Gene)
Chr6 P08023 (UniProt | EBI)
NM_001031229 (RefSeq)
zebrafish acta1a 550445 (Entrez Gene)
Chr1 NP_001017750 (RefSeq)
NM_001017750 (RefSeq)
frog, western clawed acta1 448346 (Entrez Gene)
Chr5 NP_001006709 (RefSeq)
NM_001006708 (RefSeq)
MGC75582 394982 (Entrez Gene)
Chr1 P20399 (UniProt | EBI)
NM_204024 (RefSeq)
macaque, rhesus ACTA2 100427024 (Entrez Gene)
Chr9 NP_001245001 (RefSeq)
NM_001258072 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory