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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PMS2 HGNC:9122 (HGNC)
5395 (Entrez Gene)
600259 (OMIM)
PMS2 (MyGene.info)
HGNC homology
Chr7 p22.1 Chr7:5970925-6009106 (-)
Lynch syndrome
P54278 (UniProt | EBI)
NM_001322012 (RefSeq)
mouse Pms2 MGI:104288 (MGI)
18861 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 82.82 cM Chr5:143909964-143933968 (+)
OTTMUSG00000054938 (VEGA)
OTTMUSP00000031008 (VEGA)
OTTMUST00000062771 (VEGA)
chimpanzee PMS2 463257 (Entrez Gene)
Chr7 XP_016814143 (RefSeq)
cattle PMS2 527039 (Entrez Gene)
Chr25 NP_001192867 (RefSeq)
NM_001205938 (RefSeq)
dog PMS2 479751 (Entrez Gene)
Chr6 XP_013969771 (RefSeq)
zebrafish pms2 565276 (Entrez Gene)
Chr12 XP_021335962 (RefSeq)
frog, western clawed pms2 100490402 (Entrez Gene)
Chr9 XP_002932025 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory