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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ERCC6 HGNC:3438 (HGNC)
2074 (Entrez Gene)
609413 (OMIM)
ERCC6 (MyGene.info)
HGNC homology
Chr10 q11.23 Chr10:49454480-49539538 (-)
age related macular degeneration 5
Cockayne syndrome
lung cancer
UV-sensitive syndrome
Q03468 (UniProt | EBI)
NM_001277059 (RefSeq)
mouse Ercc6 MGI:1100494 (MGI)
319955 (Entrez Gene)
Gene Tree
HGNC homology
Chr14 19.4 cM Chr14:32513521-32580990 (+)
Cockayne syndrome
ENSMUSG00000054051 (Ensembl Gene Model)
ENSMUSP00000066256 (Ensembl)
ENSMUST00000066807 (Ensembl)
rat Ercc6 306274 (Entrez Gene)
Chr16 p16 NP_001100766 (RefSeq)
NM_001107296 (RefSeq)
chimpanzee ERCC6 101058892 (Entrez Gene)
Chr10 XP_009438634 (RefSeq)
cattle ERCC6 522908 (Entrez Gene)
Chr28 NP_001178272 (RefSeq)
NM_001191343 (RefSeq)
dog ERCC6 477747 (Entrez Gene)
Chr28 XP_534944 (RefSeq)
chicken ERCC6 423785 (Entrez Gene)
Chr6 XP_004942196 (RefSeq)
zebrafish ercc6 560477 (Entrez Gene)
Chr13 XP_017214320 (RefSeq)
macaque, rhesus ERCC6 710153 (Entrez Gene)
Chr9 XP_015002505 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory