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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
133552

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ERCC6 HGNC:3438 (HGNC)
2074 (Entrez Gene)
609413 (OMIM)
Chr10 q11.23 Chr10:49454480-49539123 (-)
GRCh38
Cerebrooculofacioskeletal Syndrome 1; COFS1
Cockayne Syndrome B; CSB
De Sanctis-Cacchione Syndrome
Lung Cancer
Macular Degeneration, Age-Related, 5; ARMD5
Uv-Sensitive Syndrome 1; UVSS1
Q03468 (UniProt | EBI)
NM_000124 (RefSeq)
mouse Ercc6 MGI:1100494 (MGI)
319955 (Entrez Gene)
Gene Tree
VISTA-Point
Chr14 19.4 cM Chr14:32513521-32580989 (+)
GRCm38
Cockayne Syndrome B; CSB
ENSMUSG00000054051 (Ensembl Gene Model)
ENSMUSP00000066256 (Ensembl)
ENSMUST00000066807 (Ensembl)
rat Ercc6 306274 (Entrez Gene)
Chr16 p16 NP_001100766 (RefSeq)
NM_001107296 (RefSeq)
chimpanzee LOC101058892 101058892 (Entrez Gene)
Chr10 XP_003954268 (RefSeq)
rhesus macaque ERCC6 710153 (Entrez Gene)
Chr9 XP_001107536 (RefSeq)
cattle ERCC6 522908 (Entrez Gene)
Chr28 NP_001178272 (RefSeq)
NM_001191343 (RefSeq)
dog ERCC6 477747 (Entrez Gene)
Chr28 XP_534944 (RefSeq)
chicken ERCC6 423785 (Entrez Gene)
Chr6 XP_421656 (RefSeq)
zebrafish ercc6 560477 (Entrez Gene)
Chr13 XP_688972 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory