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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CAV1 HGNC:1527 (HGNC)
857 (Entrez Gene)
601047 (OMIM)
Caveolin 1 (MyGene.info)
HGNC homology
Chr7 q31.2 Chr7:116524785-116561185 (+)
congenital generalized lipodystrophy type 3
primary pulmonary hypertension
Q03135 (UniProt | EBI)
NM_001172897 (RefSeq)
mouse Cav1 MGI:102709 (MGI)
12389 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 7.73 cM Chr6:17306335-17341452 (+)
Alzheimer's disease
breast cancer
hypertrophic cardiomyopathy
OTTMUSG00000024023 (VEGA)
OTTMUSP00000028492 (VEGA)
OTTMUST00000058732 (VEGA)
rat Cav1 25404 (Entrez Gene)
Chr4 q21 P41350 (UniProt | EBI)
NM_133651 (RefSeq)
chimpanzee CAV1 463670 (Entrez Gene)
Chr7 Q2QLF2 (UniProt | EBI)
NM_001135818 (RefSeq)
cattle CAV1 281040 (Entrez Gene)
Chr4 P79132 (UniProt | EBI)
NM_174004 (RefSeq)
dog CAV1 403980 (Entrez Gene)
Chr14 P33724 (UniProt | EBI)
NM_001003296 (RefSeq)
chicken CAV1 373996 (Entrez Gene)
Chr1 P35431 (UniProt | EBI)
NM_001105664 (RefSeq)
zebrafish cav1 323695 (Entrez Gene)
Chr25 NP_001019333 (RefSeq)
NM_001024162 (RefSeq)
frog, western clawed cav1 548467 (Entrez Gene)
Chr3 NP_001015750 (RefSeq)
NM_001015750 (RefSeq)
macaque, rhesus CAV1 704449 (Entrez Gene)
Chr3 NP_001162085 (RefSeq)
NM_001168614 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory