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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CARS1 HGNC:1493 (HGNC)
833 (Entrez Gene)
123859 (OMIM)
HGNC homology
Chr11 p15.4 Chr11:3000922-3057451 (-)
P49589 (UniProt | EBI)
NM_139273 (RefSeq)
mouse Cars MGI:1351477 (MGI)
27267 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 88.25 cM Chr7:143557230-143600090 (-)
27267 (NCBI Gene Model)
Q9ER72 (UniProt | EBI)
NM_013742 (RefSeq)
rat Cars 293638 (Entrez Gene)
Chr1 q42 NP_001099789 (RefSeq)
NM_001106319 (RefSeq)
chimpanzee CARS1 450962 (Entrez Gene)
Chr11 XP_001155829 (RefSeq)
cattle CARS1 515715 (Entrez Gene)
Chr29 NP_001096719 (RefSeq)
NM_001103249 (RefSeq)
dog CARS1 475998 (Entrez Gene)
Chr18 XP_005631412 (RefSeq)
chicken CARS 423086 (Entrez Gene)
Chr5 Q5F408 (UniProt | EBI)
NM_001012583 (RefSeq)
zebrafish cars1 368284 (Entrez Gene)
Chr7 NP_001112372 (RefSeq)
NM_001118900 (RefSeq)
frog, western clawed cars1 496832 (Entrez Gene)
ChrUN Q5M7N8 (UniProt | EBI)
NM_001011365 (RefSeq)
macaque, rhesus CARS1 706502 (Entrez Gene)
Chr14 NP_001253255 (RefSeq)
NM_001266326 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory