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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MYLK2 HGNC:16243 (HGNC)
85366 (Entrez Gene)
606566 (OMIM)
MYLK2 (MyGene.info)
HGNC homology
Chr20 q11.21 Chr20:31819375-31834697 (+)
hypertrophic cardiomyopathy 1
Q9H1R3 (UniProt | EBI)
NM_033118 (RefSeq)
mouse Mylk2 MGI:2139434 (MGI)
228785 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 75.41 cM Chr2:152911352-152923068 (+)
ENSMUSG00000027470 (Ensembl Gene Model)
ENSMUSP00000028970 (Ensembl)
ENSMUST00000028970 (Ensembl)
rat Mylk2 117558 (Entrez Gene)
Chr3 q41 P20689 (UniProt | EBI)
NM_057209 (RefSeq)
chimpanzee MYLK2 742591 (Entrez Gene)
Chr20 XP_003316951 (RefSeq)
cattle MYLK2 533378 (Entrez Gene)
Chr13 A4IFM7 (UniProt | EBI)
NM_001083719 (RefSeq)
dog MYLK2 477187 (Entrez Gene)
Chr24 XP_005634973 (RefSeq)
chicken MYLK2 396356 (Entrez Gene)
Chr20 NP_990723 (RefSeq)
NM_205392 (RefSeq)
macaque, rhesus MYLK2 712830 (Entrez Gene)
Chr10 XP_028684125 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory