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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
132

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GCH1 HGNC:4193 (HGNC)
2643 (Entrez Gene)
600225 (OMIM)
Chr14 q22.1-q22.2 Chr14:54842005-54902885 (-)
GRCh38
Dystonia, Dopa-Responsive; DRD
Hyperphenylalaninemia, Bh4-Deficient, B; HPABH4B
P30793 (UniProt | EBI)
NM_000161 (RefSeq)
mouse Gch1 MGI:95675 (MGI)
14528 (Entrez Gene)
Gene Tree
VISTA-Point
Chr14 24.6 cM Chr14:47153895-47189402 (-)
GRCm38
14528 (NCBI Gene Model)
Q05915 (UniProt | EBI)
NM_008102 (RefSeq)
rat Gch1 29244 (Entrez Gene)
Chr15 p14 P22288 (UniProt | EBI)
NM_024356 (RefSeq)
chimpanzee GCH1 743728 (Entrez Gene)
Chr14 XP_001161570 (RefSeq)
rhesus macaque GCH1 695675 (Entrez Gene)
Chr7 XP_001087249 (RefSeq)
cattle GCH1 286815 (Entrez Gene)
Chr10 XP_001251705 (RefSeq)
dog GCH1 609393 (Entrez Gene)
Chr8 XP_005623474 (RefSeq)
chicken GCH1 396146 (Entrez Gene)
Chr5 P50141 (UniProt | EBI)
NM_205223 (RefSeq)
zebrafish gch2 64263 (Entrez Gene)
Chr12 NP_571742 (RefSeq)
NM_131667 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory