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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SIMC1 HGNC:24779 (HGNC)
375484 (Entrez Gene)
618102 (OMIM)
HGNC homology
Chr5 q35.2 Chr5:176238359-176345991 (+)
Q8NDZ2 (UniProt | EBI)
NM_001308200 (RefSeq)
mouse Simc1 MGI:2442599 (MGI)
319719 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 28.74 cM Chr13:54503779-54551290 (+)
ENSMUSG00000043183 (Ensembl Gene Model)
ENSMUSP00000113676 (Ensembl)
ENSMUST00000121401 (Ensembl)
rat Simc1 100361684 (Entrez Gene)
Chr17 F1LWT0 (UniProt | EBI)
chimpanzee SIMC1 735842 (Entrez Gene)
Chr5 XP_016809750 (RefSeq)
cattle SIMC1 100336733 (Entrez Gene)
Chr10 XP_002690456 (RefSeq)
dog SIMC1 489106 (Entrez Gene)
Chr4 XP_038390628 (RefSeq)
macaque, rhesus SIMC1 701880 (Entrez Gene)
Chr6 XP_014996948 (RefSeq)
NM_001193868 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory