About   Help   FAQ
Vertebrate Homology Class
Class ID
HomoloGene (Release 67, Dec 12, 2012)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
select all deselect all Go
human APP HGNC:620 (HGNC)
351 (Entrez Gene)
104760 (OMIM)
Chr21 q21.3 Chr21:25880550-26171128 (-)
Alzheimer Disease; AD
Cerebral Amyloid Angiopathy, App-Related
P05067 (UniProt | EBI)
NM_000484 (RefSeq)
mouse App MGI:88059 (MGI)
11820 (Entrez Gene)
Gene Tree
Chr16 46.92 cM Chr16:84954440-85173707 (-)
Alzheimer Disease; AD
ENSMUSG00000022892 (Ensembl Gene Model)
ENSMUSP00000005406 (Ensembl)
ENSMUST00000005406 (Ensembl)
zebrafish appb 170846 (Entrez Gene)
Chr9 NP_690842 (RefSeq)
NM_152886 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 5.17
The Jackson Laboratory