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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TTN HGNC:12403 (HGNC)
7273 (Entrez Gene)
188840 (OMIM)
HGNC homology
Chr2 q31 Chr2:178525989-178830754 (-)
Cardiomyopathy, Dilated, 1G; CMD1G
Cardiomyopathy, Familial Hypertrophic, 9; CMH9
Hereditary Myopathy with Early Respiratory Failure; HMERF
Muscular Dystrophy, Limb-Girdle, Type 2J; LGMD2J
Myopathy, Early-Onset, with Fatal Cardiomyopathy
Tibial Muscular Dystrophy, Tardive
Q8WZ42 (UniProt | EBI)
NM_001267550 (RefSeq)
mouse Ttn MGI:98864 (MGI)
22138 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 45.13 cM Chr2:76703980-76982547 (-)
Cardiomyopathy, Dilated, 1G; CMD1G
Muscular Dystrophy, Limb-Girdle, Type 2J; LGMD2J
Tibial Muscular Dystrophy, Tardive
OTTMUSG00000013134 (VEGA)
OTTMUSP00000016107 (VEGA)
OTTMUST00000035892 (VEGA)
rat Ttn 84015 (Entrez Gene)
Chr3 q23 XP_008760200 (RefSeq)
rhesus macaque TTN 703527 (Entrez Gene)
Chr12 XP_002808058 (RefSeq)
cattle TTN 540561 (Entrez Gene)
Chr2 q21 XP_010800172 (RefSeq)
dog TTN 478820 (Entrez Gene)
Chr36 XP_013966159 (RefSeq)
chicken TTN 424126 (Entrez Gene)
Chr7 XP_004942758 (RefSeq)
zebrafish ttna 317731 (Entrez Gene)
Chr9 XP_009303204 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory