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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human WNK4 HGNC:14544 (HGNC)
65266 (Entrez Gene)
601844 (OMIM)
HGNC homology
Chr17 q21.2 Chr17:42779673-42797066 (+)
Pseudohypoaldosteronism, Type IIB; PHA2B
Q96J92 (UniProt | EBI)
NM_001321299 (RefSeq)
mouse Wnk4 MGI:1917097 (MGI)
69847 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 64.51 cM Chr11:101260567-101277409 (+)
Gitelman Syndrome; GTLMNS
Pseudohypoaldosteronism, Type IIA; PHA2A
Pseudohypoaldosteronism, Type IIB; PHA2B
OTTMUSG00000002761 (VEGA)
OTTMUSP00000002621 (VEGA)
OTTMUST00000005511 (VEGA)
rat Wnk4 287715 (Entrez Gene)
Chr10 q32.1 Q7TPK6 (UniProt | EBI)
NM_175579 (RefSeq)
chimpanzee WNK4 454699 (Entrez Gene)
Chr17 XP_009430404 (RefSeq)
rhesus macaque WNK4 707820 (Entrez Gene)
Chr16 XP_014975276 (RefSeq)
cattle WNK4 100849076 (Entrez Gene)
Chr19 XP_005220862 (RefSeq)
dog WNK4 490959 (Entrez Gene)
Chr9 XP_548082 (RefSeq)
chicken WNK4 777580 (Entrez Gene)
Chr27 XP_015155095 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory