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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CFB HGNC:1037 (HGNC)
629 (Entrez Gene)
138470 (OMIM)
HGNC homology
Chr6 p21.3 Chr6:31945944-31952084 (+)
Complement Factor B Deficiency; CFBD
Hemolytic Uremic Syndrome, Atypical, Susceptibility to, 4; AHUS4
Macular Degeneration, Age-Related, 14; ARMD14
P00751 (UniProt | EBI)
NM_001710 (RefSeq)
mouse Cfb MGI:105975 (MGI)
14962 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 18.41 cM Chr17:34856374-34862518 (-)
OTTMUSG00000034004 (VEGA)
OTTMUSP00000046418 (VEGA)
OTTMUST00000085838 (VEGA)
rat Cfb 294257 (Entrez Gene)
Chr20 p12 NP_997631 (RefSeq)
NM_212466 (RefSeq)
chimpanzee CFB 494140 (Entrez Gene)
Chr6 Q864W0 (UniProt | EBI)
NM_001009169 (RefSeq)
rhesus macaque CFB 716809 (Entrez Gene)
Chr4 XP_014991515 (RefSeq)
cattle CFB 514076 (Entrez Gene)
Chr23 P81187 (UniProt | EBI)
NM_001040526 (RefSeq)
dog CFB 100688056 (Entrez Gene)
Chr12 XP_003431724 (RefSeq)
western clawed frog cfb 100491419 (Entrez Gene)
ChrUN XP_002943021 (RefSeq)
zebrafish bfb 30489 (Entrez Gene)
Chr21 NP_571316 (RefSeq)
NM_131241 (RefSeq)
cfb 30604 (Entrez Gene)
Chr21 NP_571413 (RefSeq)
NM_131338 (RefSeq)
zgc:158446 792472 (Entrez Gene)
Chr21 NP_001077327 (RefSeq)
NM_001083858 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory