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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TXN HGNC:12435 (HGNC)
7295 (Entrez Gene)
187700 (OMIM)
Thioredoxin (MyGene.info)
HGNC homology
Chr9 q31.3 Chr9:110243812-110256640 (-)
P10599 (UniProt | EBI)
NM_001244938 (RefSeq)
mouse Txn1 MGI:98874 (MGI)
22166 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 31.87 cM Chr4:57943373-57956411 (-)
22166 (NCBI Gene Model)
P10639 (UniProt | EBI)
NM_011660 (RefSeq)
rat Txn1 116484 (Entrez Gene)
Chr5 q24 P11232 (UniProt | EBI)
NM_053800 (RefSeq)
chimpanzee TXN 740248 (Entrez Gene)
Chr9 XP_001142154 (RefSeq)
cattle TXN 280950 (Entrez Gene)
Chr8 O97680 (UniProt | EBI)
NM_173968 (RefSeq)
dog LOC474798 474798 (Entrez Gene)
Chr11 XP_022281407 (RefSeq)
chicken TXN 396437 (Entrez Gene)
ChrZ P08629 (UniProt | EBI)
NM_205453 (RefSeq)
zebrafish txn 436734 (Entrez Gene)
Chr7 NP_001002461 (RefSeq)
NM_001002461 (RefSeq)
zgc:56493 336637 (Entrez Gene)
Chr1 NP_956317 (RefSeq)
NM_200023 (RefSeq)
frog, western clawed LOC100170420 100170420 (Entrez Gene)
Chr1 NP_001123670 (RefSeq)
NM_001130198 (RefSeq)
macaque, rhesus LOC693792 693792 (Entrez Gene)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory