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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CYP11B1 HGNC:2591 (HGNC)
1584 (Entrez Gene)
610613 (OMIM)
Steroid 11-beta-hydroxylase (MyGene.info)
HGNC homology
Chr8 q24.3 Chr8:142872354-142879839 (-)
congenital adrenal hyperplasia
glucocorticoid-remediable aldosteronism
P15538 (UniProt | EBI)
NM_000497 (RefSeq)
mouse Cyp11b2 MGI:88584 (MGI)
13072 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 34.29 cM Chr15:74851010-74856318 (-)
13072 (NCBI Gene Model)
P15539 (UniProt | EBI)
NM_009991 (RefSeq)
rat Cyp11b2 24294 (Entrez Gene)
Chr7 q34 P30099 (UniProt | EBI)
NM_012538 (RefSeq)
chimpanzee CYP11B1 464437 (Entrez Gene)
Chr8 XP_024201098 (RefSeq)
zebrafish cyp11c1 791124 (Entrez Gene)
Chr16 NP_001073673 (RefSeq)
NM_001080204 (RefSeq)
frog, western clawed LOC101731070 101731070 (Entrez Gene)
ChrUN XP_017945850 (RefSeq)
macaque, rhesus CYP11B1 695793 (Entrez Gene)
Chr8 NP_001180667 (RefSeq)
NM_001193738 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory