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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NPL HGNC:16781 (HGNC)
80896 (Entrez Gene)
611412 (OMIM)
HGNC homology
Chr1 q25.3 Chr1:182789449-182830384 (+)
Q9BXD5 (UniProt | EBI)
NM_001200050 (RefSeq)
mouse Npl MGI:1921341 (MGI)
74091 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 65.38 cM Chr1:153503015-153550045 (-)
OTTMUSG00000049716 (VEGA)
OTTMUSP00000068454 (VEGA)
OTTMUST00000126636 (VEGA)
rat Npl 304860 (Entrez Gene)
Chr13 q21 Q66H59 (UniProt | EBI)
NM_001013984 (RefSeq)
chimpanzee NPL 457567 (Entrez Gene)
Chr1 NP_001233421 (RefSeq)
NM_001246492 (RefSeq)
cattle NPL 507597 (Entrez Gene)
Chr16 Q29RY9 (UniProt | EBI)
NM_001045978 (RefSeq)
dog NPL 490313 (Entrez Gene)
Chr7 XP_022276667 (RefSeq)
chicken NPL 429074 (Entrez Gene)
Chr8 Q5ZKD4 (UniProt | EBI)
NM_001031560 (RefSeq)
zebrafish LOC100535292 100535292 (Entrez Gene)
npl 100148292 (Entrez Gene)
Chr8 Q6NYR8 (UniProt | EBI)
NM_207051 (RefSeq)
frog, western clawed npl 496638 (Entrez Gene)
Chr4 Q5M905 (UniProt | EBI)
NM_001011207 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory