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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPEN HGNC:17575 (HGNC)
23013 (Entrez Gene)
613484 (OMIM)
SPEN (MyGene.info)
HGNC homology
Chr1 p36.21-p36.13 Chr1:15847864-15940455 (+)
Q96T58 (UniProt | EBI)
NM_015001 (RefSeq)
mouse Spen MGI:1891706 (MGI)
56381 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 74.26 cM Chr4:141467890-141538597 (-)
ENSMUSG00000040761 (Ensembl Gene Model)
ENSMUSP00000101412 (Ensembl)
ENSMUST00000105786 (Ensembl)
rat Spen 690911 (Entrez Gene)
Chr5 q36 NP_001258424 (RefSeq)
NM_001271495 (RefSeq)
chimpanzee SPEN 456468 (Entrez Gene)
Chr1 XP_016810245 (RefSeq)
cattle SPEN 513692 (Entrez Gene)
Chr16 XP_002694185 (RefSeq)
dog SPEN 100687765 (Entrez Gene)
Chr2 XP_022270012 (RefSeq)
macaque, rhesus SPEN 696205 (Entrez Gene)
Chr1 XP_014975354 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory