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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LCT HGNC:6530 (HGNC)
3938 (Entrez Gene)
603202 (OMIM)
HGNC homology
Chr2 q21.3 Chr2:135787840-135837200 (-)
congenital lactase deficiency
P09848 (UniProt | EBI)
NM_002299 (RefSeq)
mouse Lct MGI:104576 (MGI)
226413 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 55.8 cM Chr1:128284756-128328318 (-)
226413 (NCBI Gene Model)
NP_001074547 (RefSeq)
NM_001081078 (RefSeq)
rat Lct 116569 (Entrez Gene)
Chr13 q13 Q02401 (UniProt | EBI)
NM_053841 (RefSeq)
chimpanzee LCT 459633 (Entrez Gene)
Chr2B XP_016805242 (RefSeq)
cattle LCT 514332 (Entrez Gene)
Chr2 NP_001192716 (RefSeq)
NM_001205787 (RefSeq)
dog LCT 483898 (Entrez Gene)
Chr19 XP_022261774 (RefSeq)
chicken LCT 424294 (Entrez Gene)
Chr7 NP_001104816 (RefSeq)
NM_001111346 (RefSeq)
zebrafish lct 796436 (Entrez Gene)
Chr9 XP_021334700 (RefSeq)
frog, western clawed lct.2 100145766 (Entrez Gene)
Chr9 XP_012826388 (RefSeq)
LOC101732850 101732850 (Entrez Gene)
Chr9 XP_004917683 (RefSeq)
macaque, rhesus LCT 707761 (Entrez Gene)
Chr12 XP_014965495 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory