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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
123817

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EIF4E HGNC:3287 (HGNC)
1977 (Entrez Gene)
133440 (OMIM)
Chr4 q21-q25 Chr4:98878456-98930635 (-)
GRCh38
Autism, Susceptibility to, 19; AUTS19
P06730 (UniProt | EBI)
NM_001968 (RefSeq)
mouse Eif4e MGI:95305 (MGI)
13684 (Entrez Gene)
Gene Tree
VISTA-Point
Chr3 64.3 cM Chr3:138526191-138557599 (+)
GRCm38
13684 (NCBI Gene Model)
P63073 (UniProt | EBI)
NM_007917 (RefSeq)
rat Eif4e 117045 (Entrez Gene)
Chr2 q44 P63074 (UniProt | EBI)
NM_053974 (RefSeq)
chimpanzee EIF4E 461391 (Entrez Gene)
Chr4 NP_001233399 (RefSeq)
NM_001246470 (RefSeq)
rhesus macaque EIF4E 706751 (Entrez Gene)
Chr5 NP_001253148 (RefSeq)
NM_001266219 (RefSeq)
cattle EIF4E 281751 (Entrez Gene)
Chr6 Q9N0T5 (UniProt | EBI)
NM_174310 (RefSeq)
dog EIF4E 487870 (Entrez Gene)
Chr32 XP_544992 (RefSeq)
chicken EIF4E 422703 (Entrez Gene)
Chr4 XP_420655 (RefSeq)
western clawed frog eif4e 548663 (Entrez Gene)
ChrUN NP_001015909 (RefSeq)
NM_001015909 (RefSeq)
zebrafish eif4ea 79380 (Entrez Gene)
Chr14 Q9DFS6 (UniProt | EBI)
NM_131733 (RefSeq)
eif4eb 493617 (Entrez Gene)
Chr13 NP_001007778 (RefSeq)
NM_001007777 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory