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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EXOSC8 HGNC:17035 (HGNC)
11340 (Entrez Gene)
606019 (OMIM)
Exosome component 8 (MyGene.info)
HGNC homology
Chr13 q13.3 Chr13:37000373-37009614 (+)
Q96B26 (UniProt | EBI)
NM_181503 (RefSeq)
mouse Exosc8 MGI:1916889 (MGI)
69639 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 25.6 cM Chr3:54728679-54735364 (-)
69639 (NCBI Gene Model)
Q9D753 (UniProt | EBI)
NM_001163570 (RefSeq)
rat Exosc8 295050 (Entrez Gene)
Chr2 q26 NP_001099902 (RefSeq)
NM_001106432 (RefSeq)
chimpanzee EXOSC8 467263 (Entrez Gene)
Chr13 XP_522661 (RefSeq)
cattle EXOSC8 532080 (Entrez Gene)
Chr12 Q2KHU3 (UniProt | EBI)
NM_001079606 (RefSeq)
dog EXOSC8 477300 (Entrez Gene)
Chr25 XP_005635498 (RefSeq)
chicken EXOSC8 100858560 (Entrez Gene)
Chr1 XP_003640625 (RefSeq)
zebrafish exosc8 323016 (Entrez Gene)
Chr10 NP_001002865 (RefSeq)
NM_001002865 (RefSeq)
frog, western clawed exosc8 493300 (Entrez Gene)
Chr2 NP_001007919 (RefSeq)
NM_001007918 (RefSeq)
macaque, rhesus EXOSC8 695071 (Entrez Gene)
Chr17 NP_001247467 (RefSeq)
NM_001260538 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory