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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
121702

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACTA1 HGNC:129 (HGNC)
58 (Entrez Gene)
102610 (OMIM)
Chr1 q42.13 Chr1:229431245-229434096 (-)
GRCh38
Myopathy, Congenital, with Fiber-Type Disproportion; CFTD
Nemaline Myopathy 3; NEM3
P68133 (UniProt | EBI)
NM_001100 (RefSeq)
mouse Acta1 MGI:87902 (MGI)
11459 (Entrez Gene)
Gene Tree
VISTA-Point
Chr8 72.26 cM Chr8:123891767-123894736 (-)
GRCm38
Nemaline Myopathy 3; NEM3
11459 (NCBI Gene Model)
P68134 (UniProt | EBI)
NM_001272041 (RefSeq)
rat Acta1 29437 (Entrez Gene)
Chr19 q12 P68136 (UniProt | EBI)
NM_019212 (RefSeq)
chimpanzee ACTA1 100609865 (Entrez Gene)
Chr1 XP_003308856 (RefSeq)
rhesus macaque ACTA1 100426612 (Entrez Gene)
Chr1 XP_002802172 (RefSeq)
dog ACTA1 488984 (Entrez Gene)
Chr4 XP_005618896 (RefSeq)
chicken ACTA1 421534 (Entrez Gene)
Chr3 P68139 (UniProt | EBI)
NM_001031063 (RefSeq)
zebrafish acta1b 407658 (Entrez Gene)
Chr13 NP_999949 (RefSeq)
NM_214784 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory