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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACTA1 HGNC:129 (HGNC)
58 (Entrez Gene)
102610 (OMIM)
HGNC homology
Chr1 q42.13 Chr1:229431245-229434096 (-)
congenital fiber-type disproportion
nemaline myopathy 3
P68133 (UniProt | EBI)
NM_001100 (RefSeq)
mouse Acta1 MGI:87902 (MGI)
11459 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 72.26 cM Chr8:123891769-123894751 (-)
nemaline myopathy 3
OTTMUSG00000062000 (VEGA)
OTTMUSP00000078510 (VEGA)
OTTMUST00000151381 (VEGA)
rat Acta1 29437 (Entrez Gene)
Chr19 q12 P68136 (UniProt | EBI)
NM_019212 (RefSeq)
chimpanzee ACTA1 100609865 (Entrez Gene)
Chr1 XP_016796083 (RefSeq)
cattle ACTA1 281592 (Entrez Gene)
Chr28 P68138 (UniProt | EBI)
NM_174225 (RefSeq)
dog ACTA1 488984 (Entrez Gene)
Chr4 XP_005618896 (RefSeq)
chicken ACTA1 421534 (Entrez Gene)
Chr3 P68139 (UniProt | EBI)
NM_001031063 (RefSeq)
zebrafish acta1b 407658 (Entrez Gene)
Chr13 NP_999949 (RefSeq)
NM_214784 (RefSeq)
frog, western clawed act3 394673 (Entrez Gene)
Chr4 Q6P8G3 (UniProt | EBI)
NM_203745 (RefSeq)
macaque, rhesus ACTA1 100426612 (Entrez Gene)
Chr1 XP_002802173 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory