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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LYZ HGNC:6740 (HGNC)
4069 (Entrez Gene)
153450 (OMIM)
Lysozyme (MyGene.info)
HGNC homology
Chr12 q15 Chr12:69348354-69354233 (+)
familial visceral amyloidosis
P61626 (UniProt | EBI)
NM_000239 (RefSeq)
mouse Lyz1 MGI:96902 (MGI)
17110 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 65.35 cM Chr10:117287797-117292868 (-)
ENSMUSG00000069515 (Ensembl Gene Model)
ENSMUSP00000089800 (Ensembl)
ENSMUST00000092162 (Ensembl)
Lyz2 MGI:96897 (MGI)
17105 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 65.34 cM Chr10:117277541-117282272 (-)
17105 (NCBI Gene Model)
P08905 (UniProt | EBI)
NM_017372 (RefSeq)
rat Lyz2 25211 (Entrez Gene)
Chr7 q22 P00697 (UniProt | EBI)
NM_012771 (RefSeq)
chimpanzee LYZ 450190 (Entrez Gene)
Chr12 P61628 (UniProt | EBI)
NM_001009073 (RefSeq)
cattle LYZ 777776 (Entrez Gene)
Chr5 P80189 (UniProt | EBI)
NM_001078159 (RefSeq)
dog LYZ 474442 (Entrez Gene)
Chr10 P81709 (UniProt | EBI)
NM_001300876 (RefSeq)
chicken LYZ 396218 (Entrez Gene)
Chr1 P00698 (UniProt | EBI)
NM_205281 (RefSeq)
frog, western clawed lyz 100492798 (Entrez Gene)
Chr3 XP_002938553 (RefSeq)
macaque, rhesus LYZ 718361 (Entrez Gene)
Chr11 P30201 (UniProt | EBI)
NM_001101733 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory