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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IL18 HGNC:5986 (HGNC)
3606 (Entrez Gene)
600953 (OMIM)
Interleukin 18 (MyGene.info)
HGNC homology
Chr11 q23.1 Chr11:112143251-112164117 (-)
Q14116 (UniProt | EBI)
NM_001243211 (RefSeq)
mouse Il18 MGI:107936 (MGI)
16173 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 27.75 cM Chr9:50554827-50581840 (+)
atopic dermatitis
ENSMUSG00000039217 (Ensembl Gene Model)
ENSMUSP00000151002 (Ensembl)
ENSMUST00000214117 (Ensembl)
rat Il18 29197 (Entrez Gene)
Chr8 q23 P97636 (UniProt | EBI)
NM_019165 (RefSeq)
chimpanzee IL18 739011 (Entrez Gene)
Chr11 XP_016777472 (RefSeq)
cattle IL18 281249 (Entrez Gene)
Chr15 Q9TU73 (UniProt | EBI)
NM_174091 (RefSeq)
dog IL18 403796 (Entrez Gene)
Chr5 Q9XSR0 (UniProt | EBI)
NM_001003169 (RefSeq)
macaque, rhesus IL18 574151 (Entrez Gene)
Chr14 NP_001028006 (RefSeq)
NM_001032834 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory