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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TTI2 HGNC:26262 (HGNC)
80185 (Entrez Gene)
614426 (OMIM)
HGNC homology
Chr8 p12 Chr8:33498509-33513601 (-)
autosomal recessive non-syndromic intellectual disability
Q6NXR4 (UniProt | EBI)
NM_001330505 (RefSeq)
mouse Tti2 MGI:2384576 (MGI)
234138 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 18.03 cM Chr8:31150316-31164703 (+)
234138 (NCBI Gene Model)
Q8BGV4 (UniProt | EBI)
NR_103719 (RefSeq)
rat Tti2 290811 (Entrez Gene)
Chr16 q12.3 Q66H56 (UniProt | EBI)
NM_001013883 (RefSeq)
chimpanzee TTI2 747397 (Entrez Gene)
Chr8 NP_001233468 (RefSeq)
NM_001246539 (RefSeq)
cattle TTI2 535350 (Entrez Gene)
Chr27 NP_001092539 (RefSeq)
NM_001099069 (RefSeq)
dog TTI2 608405 (Entrez Gene)
Chr16 XP_005629935 (RefSeq)
chicken TTI2 426923 (Entrez Gene)
Chr22 XP_004947633 (RefSeq)
zebrafish tti2 100334230 (Entrez Gene)
Chr8 XP_002663251 (RefSeq)
frog, western clawed tti2 100487242 (Entrez Gene)
Chr3 XP_002932740 (RefSeq)
macaque, rhesus TTI2 696776 (Entrez Gene)
Chr8 NP_001180731 (RefSeq)
NM_001193802 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory