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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LRRC8E HGNC:26272 (HGNC)
80131 (Entrez Gene)
612891 (OMIM)
LRRC8E (MyGene.info)
HGNC homology
Chr19 p13.2 Chr19:7888505-7902023 (+)
Q6NSJ5 (UniProt | EBI)
NM_025061 (RefSeq)
mouse Lrrc8e MGI:1919517 (MGI)
72267 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 1.99 cM Chr8:4226827-4237470 (+)
ENSMUSG00000046589 (Ensembl Gene Model)
ENSMUSP00000052055 (Ensembl)
ENSMUST00000053035 (Ensembl)
rat Lrrc8e 304203 (Entrez Gene)
Chr12 p12 Q3KRC6 (UniProt | EBI)
NM_001034139 (RefSeq)
chimpanzee LRRC8E 469115 (Entrez Gene)
Chr19 XP_003316107 (RefSeq)
cattle LRRC8E 507824 (Entrez Gene)
Chr7 NP_001192551 (RefSeq)
NM_001205622 (RefSeq)
dog LRRC8E 485003 (Entrez Gene)
Chr20 XP_005633002 (RefSeq)
frog, western clawed lrrc8e 493249 (Entrez Gene)
Chr3 Q68F79 (UniProt | EBI)
NM_001007862 (RefSeq)
macaque, rhesus LRRC8E 706394 (Entrez Gene)
Chr19 XP_001093244 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory