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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FH HGNC:3700 (HGNC)
2271 (Entrez Gene)
136850 (OMIM)
HGNC homology
Chr1 q43 Chr1:241497557-241519785 (-)
fumarase deficiency
P07954 (UniProt | EBI)
NM_000143 (RefSeq)
mouse Fh1 MGI:95530 (MGI)
14194 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 81.58 cM Chr1:175601378-175625635 (-)
14194 (NCBI Gene Model)
P97807 (UniProt | EBI)
NM_010209 (RefSeq)
rat Fh 24368 (Entrez Gene)
Chr13 q25 P14408 (UniProt | EBI)
NM_017005 (RefSeq)
chimpanzee FH 457851 (Entrez Gene)
Chr1 NP_001267172 (RefSeq)
NM_001280243 (RefSeq)
cattle FH 520260 (Entrez Gene)
Chr16 NP_001069271 (RefSeq)
NM_001075803 (RefSeq)
dog FH 480092 (Entrez Gene)
Chr7 XP_537215 (RefSeq)
chicken FH 420969 (Entrez Gene)
Chr2 NP_001006382 (RefSeq)
NM_001006382 (RefSeq)
zebrafish fh 393938 (Entrez Gene)
Chr12 Q7SX99 (UniProt | EBI)
NM_200963 (RefSeq)
frog, western clawed fh 100491219 (Entrez Gene)
Chr5 XP_002935862 (RefSeq)
macaque, rhesus FH 707542 (Entrez Gene)
Chr1 XP_001094968 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory