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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FLNA HGNC:3754 (HGNC)
2316 (Entrez Gene)
300017 (OMIM)
ChrX q28 ChrX:154348529-154374638 (-)
Cardiac Valvular Dysplasia, X-Linked; CVD1
FG Syndrome 2; FGS2
Frontometaphyseal Dysplasia; FMD
Heterotopia, Periventricular, Ehlers-Danlos Variant
Heterotopia, Periventricular, X-Linked Dominant
Intestinal Pseudoobstruction, Neuronal, Chronic Idiopathic, X-Linked
Melnick-Needles Syndrome; MNS
Otopalatodigital Syndrome, Type II; OPD2
Otopalatodigital Syndrome, Type I; OPD1
Terminal Osseous Dysplasia; TOD
P21333 (UniProt | EBI)
NM_001456 (RefSeq)
mouse Flna MGI:95556 (MGI)
192176 (Entrez Gene)
Gene Tree
ChrX 37.89 cM ChrX:74223461-74249820 (-)
Heterotopia, Periventricular, X-Linked Dominant
Melnick-Needles Syndrome; MNS
Otopalatodigital Syndrome, Type II; OPD2
Otopalatodigital Syndrome, Type I; OPD1
OTTMUSG00000016503 (VEGA)
OTTMUSP00000017782 (VEGA)
OTTMUST00000039863 (VEGA)
rat Flna 293860 (Entrez Gene)
ChrX NP_001128071 (RefSeq)
NM_001134599 (RefSeq)
rhesus macaque FLNA 699524 (Entrez Gene)
ChrX XP_001091073 (RefSeq)
cattle FLNA 281165 (Entrez Gene)
ChrX NP_001193443 (RefSeq)
NM_001206514 (RefSeq)
dog FLNA 481084 (Entrez Gene)
ChrX XP_867483 (RefSeq)
chicken FLNA 395261 (Entrez Gene)
ChrUN NP_989905 (RefSeq)
NM_204574 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory