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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C10orf2 HGNC:1160 (HGNC)
56652 (Entrez Gene)
606075 (OMIM)
HGNC homology
Chr10 q24 Chr10:100987378-100994403 (+)
Mitochondrial DNA Depletion Syndrome 7 (hepatocerebral Type); MTDPS7
Perrault Syndrome 5; PRLTS5
Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant 3; PEOA3
Sensory Ataxic Neuropathy, Dysarthria, and Ophthalmoparesis; SANDO
Q96RR1 (UniProt | EBI)
NM_001163813 (RefSeq)
mouse Peo1 MGI:2137410 (MGI)
226153 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 38.19 cM Chr19:45006558-45012762 (+)
Parkinson Disease, Mitochondrial
Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant 3; PEOA3
ENSMUSG00000025209 (Ensembl Gene Model)
ENSMUSP00000026227 (Ensembl)
ENSMUST00000026227 (Ensembl)
rat Peo1 309441 (Entrez Gene)
Chr1 q54 NP_001101069 (RefSeq)
NM_001107599 (RefSeq)
chimpanzee C10H10orf2 745279 (Entrez Gene)
Chr10 XP_009457438 (RefSeq)
rhesus macaque C9H10orf2 710958 (Entrez Gene)
Chr9 NP_001181370 (RefSeq)
NM_001194441 (RefSeq)
cattle C26H10orf2 538467 (Entrez Gene)
Chr26 NP_001091933 (RefSeq)
NM_001098463 (RefSeq)
dog C28H10orf2 486845 (Entrez Gene)
Chr28 XP_005637682 (RefSeq)
chicken C10orf2 425626 (Entrez Gene)
Chr6 Q5ZIW1 (UniProt | EBI)
NM_001031344 (RefSeq)
western clawed frog c10orf2 100491229 (Entrez Gene)
ChrUN XP_002938766 (RefSeq)
zebrafish peo1 100330448 (Entrez Gene)
Chr12 NP_001264527 (RefSeq)
NM_001277598 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory