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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TWNK HGNC:1160 (HGNC)
56652 (Entrez Gene)
606075 (OMIM)
PEO1 (MyGene.info)
HGNC homology
Chr10 q24.31 Chr10:100987527-100994403 (+)
infantile onset spinocerebellar ataxia
Q96RR1 (UniProt | EBI)
NM_001163812 (RefSeq)
mouse Twnk MGI:2137410 (MGI)
226153 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 38.19 cM Chr19:45006558-45012762 (+)
Parkinson's disease
ENSMUSG00000025209 (Ensembl Gene Model)
ENSMUSP00000026227 (Ensembl)
ENSMUST00000026227 (Ensembl)
rat Twnk 309441 (Entrez Gene)
Chr1 q54 NP_001101069 (RefSeq)
NM_001107599 (RefSeq)
chimpanzee TWNK 745279 (Entrez Gene)
Chr10 XP_016774626 (RefSeq)
cattle TWNK 538467 (Entrez Gene)
Chr26 NP_001091933 (RefSeq)
NM_001098463 (RefSeq)
dog TWNK 486845 (Entrez Gene)
Chr28 XP_022267821 (RefSeq)
chicken TWNK 425626 (Entrez Gene)
Chr6 Q5ZIW1 (UniProt | EBI)
NM_001031344 (RefSeq)
zebrafish twnk 100330448 (Entrez Gene)
Chr12 NP_001264527 (RefSeq)
NM_001277598 (RefSeq)
frog, western clawed twnk 100491229 (Entrez Gene)
Chr7 XP_002938766 (RefSeq)
macaque, rhesus TWNK 710958 (Entrez Gene)
Chr9 NP_001181370 (RefSeq)
NM_001194441 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory